Anhydrotetracycline hydrochloride ( —— )

产品货号. M27420 CAS No. 13803-65-1

脱水四环素（盐酸盐）是广谱四环素破坏酶的有效竞争性抑制剂。

纯度: >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

规格	价格/人民币	库存	数量
5MG	￥616	有现货
10MG	￥1037	有现货
25MG	￥2130	有现货
50MG	￥3548	有现货
100MG	￥5144	有现货
500MG	￥10692	有现货
1G	获取报价	有现货

产品询价大包装询价加入购物车

生物学信息

产品名称

Anhydrotetracycline hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

脱水四环素（盐酸盐）是广谱四环素破坏酶的有效竞争性抑制剂。
产品描述

Anhydrotetracycline (hydrochloride) is a potent competitive inhibitor of broad-spectrum tetracycline destructase enzymes.(In Vitro):Anhydrotetracycline (hydrochloride), a tetracycline biosynthetic precursor, inhibited Tet50, TetX, TetX-3 degradations of tetracyclines with the IC50s of 210 μM, 41 μM and 3 μM,respectively. Anhydrotetracycline (hydrochloride) inhibited Tet50, TetX, TetX-3 degradations of demeclocycline with the IC50s of 120 μM, 41 μM, 7 μM,respectively. Anhydrotetracycline (hydrochloride) inhibited Tet50, TetX, TetX-3 degradations of chlortetracycline with the IC50s of 210 μM, 75 μM, 26 μM,respectively.
体外实验

Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=210 μM),Tet(X) (IC50=41 μM), Tet(X)_3 (IC50=3 μM) degradations of tetracyclines. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=210 μM),Tet(X) (IC50=75 μM), Tet(X)_3 (IC50=26 μM) degradations of chlortetracycline. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=120 μM),Tet(X) (IC50=41 μM), Tet(X)_3 (IC50=7 μM) degradations of demeclocycline. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=210 μM),Tet(X) (IC50=41 μM), Tet(X)_3 (IC50=3 μM) degradations of tetracyclines. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=210 μM),Tet(X) (IC50=75 μM), Tet(X)_3 (IC50=26 μM) degradations of chlortetracycline. Anhydrotetracycline hydrochloride inhibits Tet(50) (IC50=120 μM),Tet(X) (IC50=41 μM), Tet(X)_3 (IC50=7 μM) degradations of demeclocycline.
体内实验

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同义词

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通路

GPCR/G Protein
靶点

Antibacterial
受体

——
研究领域

——
适应症

——

化学信息

CAS Number

13803-65-1
分子量

462.88
分子式

C22H23ClN2O7
纯度

>98% (HPLC)
溶解度

In Vitro:?H2O : 170 mg/mL (367.27 mM)
SMILES

O=C(C(C1=O)=C(O)C(N(C)C)C2CC3=C(C(C21O)=O)C(O)=C4C(O)=CC=CC4=C3C)N.[H]Cl
化学全称

——

运输与储存

储存条件

(-20℃)
运输条件

With Ice Pack
稳定性

≥ 2 years

参考文献

1.Yang XH, et al. Ultra-high performance liquid chromatography coupled with quadrupole/time of flight mass spectrometry based chemical profiling approach for the holistic quality control of complex Kang-Jing formula preparations. J Pharm Biomed Anal. 2016 May 30;124:319-36.

计算器

浓度计算器

摩尔计算器

分子量计算器

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